In this episode, Dr. James Tour teaches the 4th class of compounds needed for life: lipids and phospholipids, including their structures and organizational assemblies. With the thousands of different lipid structures identified in cell membranes, a discussion of whether simple lipid bilayers can be suitable cell membranes is had. Dr. Tour then looks at various syntheses as potential routes to fatty acids, bringing prebiotic relevance into the equation. With relay syntheses, chain swapping, and racemic mixtures amuck, early Earth is still left with enormous supplementary material procedures to follow, with no chemist available. When it comes to the synthesis of lipids, the luxuries of today indeed become “first world problems” in a most literal sense for those “first world years”.

Video Index:
00:00​ – Introduction
00:34 – Reasons & Intent of this Abiogenesis Series
02:48 – Lipids and Phospholipids
05:26 – Phospholipid Structure & Cellular Membrane
11:26 – Synthesis of Lipids
13:27 – Fatty Acid Proposed Routes
16:27 – Science: salad dressing wont suffice for proton gradients
21:01 – Prebiotic Earths Waldo: Chasing Relay Synthesis, Stereochemistry, and more
39:47 – Addressing Inaccurate Prebiotic Chemistry Claims
41:12 – Summary, Appeal to Origin of Life Researchers, and Whats Next

Links in this Series | Addressing Abiogenesis & Common Misconceptions
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Series Trailer:

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0 – Reasons for this Series:

1 – Introduction to Abiogenesis:

2 – Primordial Soup:

3 – Hype:

4 – Homochirality:

5 – Carbohydrates:

6 – Building Blocks of Building Blocks:

7 – Peptides:

8 – Nucleotides:

9 – Intermediate Summary & a Call to Colleagues:

10 – Lipids:

11 – Chiral-induced Spin Selectivity:

12.1 – Cell Construction & The Assembly Problem, Part 1:

12.2 – Cell Construction & The Assembly Problem, Part 2:

13 – Summary & Projections:

Organelles of a human cell by wehu.edu.au:

Illuminating the secret world of your glycans by Utrecht University:

Link to the cited video (“Elucidating the Agenda of James Tour: A Defense of Abiogenesis”) can be found in the video description of Episode 0 – “Reasons for this Series” here:

The passionate thumbnail for this video uses a still frame image taken from Dr. Tour’s video on Flash Graphene when he says “any” in the phrase “any carbon source” at 0:12:

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#Abiogenesis #JamesTour #OriginOfLife

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