Royal Truman presents cells as sophisticated information-processing systems governed by biological codes, arguing that microRNA regulation depends on tightly coordinated digital-and-analog logic. The discussion challenges naturalistic origin scenarios by focusing on genome burden, misregulation, protein infrastructure, and population-genetics hurdles.

Truman, R., Singh, A., and Borger, P., Cells Are Integrated Multiprocessing Analog Computing Devices—Part 1, Creation Research Society Quarterly 2026 62:315–330.
https://www.researchgate.net/publication/404820791_Cells_Are_Integrated_Multiprocessing_Analog_Computing_Devices-Part_1

Truman, R., Singh, A., and Borger, P., Cells Are Integrated Multiprocessing Analog Computing Devices—Part 2, Creation Research Society Quarterly 2026 62:331–344.
https://www.researchgate.net/publication/404820794_Cells_Are_Integrated_Multiprocessing_Analog_Computing_Devices-Part_2

Featuring:
Dr. James Tour
Dr. Royal Truman
Dr. Rob Stadler
Dr. Onsi Fakhouri

00:00 Intro: just-so stories and biology
03:59 Enzymes, codes, and cellular control
07:25 Recognition elements and specificity factors
10:11 Variables, values, and E-box examples
13:28 Data structures in RNA and chromosomes
16:17 Queues, translation, and overlapping codes
19:25 Is cellular code only an analogy?
22:05 Analog programming and fuzzy variables
24:32 Continuous signals in cellular programs
26:46 How microRNA regulation works
30:07 Extra genome burden for microRNA origins
33:03 Random binding and harmful misregulation
36:23 Target counts and timing problems
39:09 Population genetics of fixation
43:55 Slightly harmful mutations rarely fix
45:54 Other biological codes face same issue
47:53 Digital and analog life compared
51:21 Small RNAs vs microRNA systems
53:35 Co-option stories and waiting-time math
56:20 Species-specific microRNA challenges
58:30 Cellular sensors and downstream events
01:01:17 Critique of simplified origin stories
01:04:37 Information transfer and complexity
01:07:04 Final reflections on cellular engineering
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